Design and Analysis of Drug Combination Experiments
نویسندگان
چکیده
منابع مشابه
Design and analysis of drug combination experiments.
In this paper we present and discuss a novel, simple and easy to implement parametric modeling approach to assess synergy. An extended three parameter log-logistic model is used to analyse the data and calculate confidence intervals of the interaction indices. In addition the model corrects for the bias due to plate-location effects. The analysis is performed with PROC NLMIXED and SAS-code is p...
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ژورنال
عنوان ژورنال: Biometrical Journal
سال: 2005
ISSN: 0323-3847,1521-4036
DOI: 10.1002/bimj.200410124